International Journal of Gynecology & Obstetrics
Volume 87, Issue 2 , Pages 188-193 , November 2004

Mifepristone versus the Yuzpe regimen (PC4) for emergency contraception

Received 16 March 2004 ,Revised 1 June 2004 ,Accepted 3 June 2004.

References 

  1. WHOTask Force on Postovulatory Methods of Fertility Regulation . Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Task Force on Postovulatory Methods of Fertility Regulation. Lancet. 1998;352(9126):428–433
  2. Bagshaw SN, Edwards D, Tucker AK. Ethinyl oestradiol and d-norgestrel is an effective emergency postcoital contraceptive: a report of its use in 1200 patients in a family planning clinic. Australian and New Zealand Journal of Obstetrics and Gynaecology. 1988;28(2):137–140
  3. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT. Mifepristone (RU 486) compared with high-dose estrogen and progestogen for emergency postcoital contraception. New England Journal of Medicine. 1992;327(15):1041–1044
  4. van Santen MR, Haspels AA. A comparison of high-dose estrogens versus low-dose ethinylestradiol and norgestrel combination in postcoital interception: a study in 493 women. Fertility and Sterility. 1985;43(2):206–213
  5. Webb AM, Russell J, Elstein M. Comparison of Yuzpe regimen, danazol, and mifepristone (RU486) in oral postcoital contraception. BMJ. 1992;305(6859):927–931
  6. Yuzpe AA, Smith RP, Rademaker AW. A multicenter clinical investigation employing ethinyl estradiol combined with dl-norgestrel as postcoital contraceptive agent. Fertility and Sterility. 1982;37(4):508–513
  7. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT. Mifepristone (RU 486) compared with high-dose estrogen and progestogen for emergency postcoital contraception. New England Journal of Medicine. 1992;327(15):1041–1044
  8. WHOTask Force on Postovulatory Methods of Fertility Regulation . Comparison of three single doses of mifepristone as emergency contraception: a randomised trial. Task Force on Postovulatory Methods of Fertility Regulation. Lancet. 1999;353(9154):697–702
  9. Ashok PW, Stalder C, Wagaarachchi PT, Flett GM, Melvin L, Templeton A. A randomised study comparing a low dose of mifepristone and the Yuzpe regimen for emergency contraception. British Journal of Obstetrics and Gynaecology. 2002;109(5):553–560
  10. Makuch R, Simon R. Sample size requirements for evaluating a conservative therapy. Cancer Treatment Reports. 1978;62(7):1037–1040
  11. Ashok PW, Kidd A, Flett GM, Fitzmaurice A, Graham W, Templeton A. A randomized comparison of medical abortion and surgical vacuum aspiration at 10–13 weeks gestation. Human Reproduction. 2002;17(1):92–98
  12. Glasier A, Thong KJ, Dewar M, Mackie M, Baird DT. Mifepristone (RU 486) compared with high-dose estrogen and progestogen for emergency postcoital contraception. New England Journal of Medicine. 1992;327(15):1041–1044
  13. Ledger WL, Sweeting VM, Hillier H, Baird DT. Inhibition of ovulation by low-dose mifepristone (RU 486). Human Reproduction. 1992;7(7):945–950
  14. Liu JH, Garzo G, Morris S, Stuenkel C, Ulmann A, Yen SS. Disruption of follicular maturation and delay of ovulation after administration of the antiprogesterone RU486. Journal of Clinical Endocrinology and Metabolism. 1987;65(6):1135–1140

PII: S0020-7292(04)00238-3

doi: 10.1016/j.ijgo.2004.06.012

International Journal of Gynecology & Obstetrics
Volume 87, Issue 2 , Pages 188-193 , November 2004