International Journal of Gynecology & Obstetrics
Volume 91, Issue 3 , Pages 228-232, December 2005

Sublingual nitroglycerin for management of retained placenta

  • M. Bullarbo

      Affiliations

    • Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Göteborg, Sweden
    • Corresponding Author InformationCorresponding author. Tel.: +46 31 3434000; fax: +46 31 418717.
    • ,
  • J. Tjugum

      Affiliations

    • Department of Obstetrics and Gynecology, Förde Hospital, Förde, Norway
    • ,
  • E. Ekerhovd

      Affiliations

    • Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Göteborg, Sweden

Received 16 June 2005; received in revised form 23 August 2005; accepted 31 August 2005.

Abstract 

Objective

The aim of the study was to investigate the effect of sublingual nitroglycerin for management of retained placenta and to assess possible adverse effects of the treatment.

Method

Twenty-four women were randomly selected to receive either 1 mg nitroglycerin or placebo tablets sublingually if intravenous oxytocin and controlled umbilical cord traction had failed to expel the placenta. Success rate for delivery of placenta, blood pressure, pulse rate, blood loss, and various side effects were examined.

Result

All 12 women in the nitroglycerin group had successful delivery of placenta, while removal of placenta was successful in only one of the 12 women in the placebo group. No adverse effects of clinical importance were registered.

Conclusion

Sublingual nitroglycerin for treatment of retained placenta seems to be effective without causing serious adverse effects. However, the definite clinical value needs to be evaluated in larger series of patients.

Keywords: Nitroglycerin, Oxytocin, Retained placenta

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PII: S0020-7292(05)00486-8

doi:10.1016/j.ijgo.2005.08.020

Refers to erratum:

  • Corrigendum to “Sublingual nitroglycerin for management of retained placenta” [Int J Gynecol Obstet 91 (2005) 228–232]

    M. Bullarbo, J. Tjugum, E. Ekerhovd
    International Journal of Gynecology & Obstetrics March 2006 (Vol. 92, Issue 3, Page 337)

International Journal of Gynecology & Obstetrics
Volume 91, Issue 3 , Pages 228-232, December 2005

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