International Journal of Gynecology & Obstetrics
Volume 91, Issue 3 , Pages 228-232 , December 2005

Sublingual nitroglycerin for management of retained placenta

  • M. Bullarbo

      Affiliations

    • Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Göteborg, Sweden
    • Corresponding Author InformationCorresponding author. Tel.: +46 31 3434000; fax: +46 31 418717.
  • ,
  • J. Tjugum

      Affiliations

    • Department of Obstetrics and Gynecology, Förde Hospital, Förde, Norway
  • ,
  • E. Ekerhovd

      Affiliations

    • Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Göteborg, Sweden

Received 16 June 2005 ,Revised 23 August 2005 ,Accepted 31 August 2005.

References 

  1. Combs CA, Laros RK. Prolonged third stage of labour: morbidity and risk factors. Obstet Gynecol. 1991;77:863–867
  2. Dombrowski MP, Buttoms SF, Saleh AA, Hurd WW, Romero R. Third stage of labor: analysis of duration and clinical practice. Am J Obstet Gynecol. 1995;172:1279–1284
  3. Pipingas A, Hofmeyr GJ, Sesel KR. Umbilical vessel oxytocin administration for retained placenta: in vitro study of various techniques. Am J Obstet Gynecol. 1993;168:93–795
  4. Carroli G, Bergel E. Umbilical vein injection for management of retained placenta. In: The Cochrane Library, Issue 1. Chichester (UK): John Wiley & Sons, Ltd; 2004;
  5. Chauhan P. Volume and site of injection of oxytocin solution is important in the medical treatment of retained placenta. Int J Gynecol Obstet. 2000;70(Suppl. 1):A83
  6. Vinatier D, Dufour P, Bérard J. Utilization of intravenous nitroglycerin for obstetrical emergencies. Int J Gynecol Obstet. 1996;55:129–134
  7. Dufour P, Vinatier D, Puech F. The use of intravenous nitroglycerin for cervico-uterine relaxation: a review of the literature. Arch Gynecol Obstet. 1997;261:1–7
  8. Chedraui PA, Insuasti DF. Intravenous nitroglycerin in the management of retained placenta. Gynecol Obstet Invest. 2003;56:61–64
  9. Buhimschi I, Yallampalli C, Dong YL, Garfield RE. Involvement of the nitric oxide-cyclic guanosine monophosphate pathway in control of human uterine contractility during pregnancy. Am J Obstet Gynecol. 1995;172:1577–1584
  10. Norman JE, Ward LM, Martin W, Cameron AD, McGrath JC, Greer IA, et al. Effects of cGMP and nitric oxide donors glyceryl trinitrate and sodium nitroprusside on contractions in vitro of isolated myometrial tissue from pregnant women. J Reprod Fertil. 1997;110:249–254
  11. Ekerhovd E, Weidegård B, Brännström M, Norström A. Nitric oxide-mediated effects on myometrial contractility at term during prelabor and labor. Obstet Gynecol. 1999;93:987–994
  12. Ekerhovd E, Brännström M, Weijdegård B, Norström A. Nitric oxide synthases in the human cervix at term pregnancy and effects of nitric oxide on cervical smooth muscle contractility. Am J Obstet Gynecol. 2000;183:610–616
  13. Axemo P, Fu X, Lindberg B, Ulmsten U, Wessen A. Intravenous nitroglycerin for rapid uterine relaxation. Acta Obstet Gynecol Scand. 1998;77:50–53
  14. Peng AT, Gorman RS, Shulman SM, DeMarchis E. Intravenous nitroglycerin for uterine relaxation in the postpartum patient with retained placenta. Anesthesiology. 1989;71:172–173
  15. Desimone CA, Norris MC, Leighton BL. Intravenous nitroglycerin aids manual extraction of a retained placenta. Anesthesiology. 1990;73:787
  16. Lowenwirt IP, Zaul RM, Handwerker SM. Safety of intravenous glyceryl trinitrate in management of retained placenta. Aust N Z J Obstet Gynaecol. 1997;37:20–24
  17. Jensen KM, Dahl JB. Plasma concentrations of glyceryl trinitrate and its dinitrate metabolites after sublingual administration to volunteers. Simultaneous determination of glyceryl trinitrate and its dinitrate metabolites. Arzneimittelforschung. 1994;44:951–953
  18. Herman A, Weinraub Z, Bukovsky I, Arieli S, Zabow P, Caspi E, et al. Dynamic ultrasosnographic imaging of the third stage of labor: new perspectives into third-stage mechanisms. Am J Obstet Gynecol. 1993;168:1496–1499
  19. Farley AE, Graham CH, Smith GN. Contractile properties of human anchoring villi. Am J Physiol Regul Integr Comp Physiol. 2004;287:R680–R684
  20. Ticconi C, Zicari A, Realacci M, Di Vito M, Denora P, Narcisi M, et al. Oxytocin modulates nitric oxide generation by human fetal membranes at term. AJRI. 2004;52:185–191

PII: S0020-7292(05)00486-8

doi: 10.1016/j.ijgo.2005.08.020

International Journal of Gynecology & Obstetrics
Volume 91, Issue 3 , Pages 228-232 , December 2005