International Journal of Gynecology & Obstetrics
Volume 95, Supplement 1 , Pages S247-S257, November 2006

Quality of Life Considerations in Gynecologic Cancer

  • Richard T PENSON

      Affiliations

    • Harvard Medical School, Boston, MA, USA
    • ,
  • Lari B WENZEL

      Affiliations

    • College of Medicine University of California, Irvine, CA, USA
    • Corresponding Author InformationAddress correspondence to: Lari B. Wenzel, Ph.D., Associate Professor, Center for Health Policy Research College of Medicine, University of California Irvine, 111 Academy Suite 220, Irvine, CA 92697; Phone: 949.824.3926; Fax: 949.824.3383
    • ,
  • Ignace VERGOTE

      Affiliations

    • University Hospital Leuven, Dept. of Gynaecological Oncology, Leuven, Belgium
    • ,
  • David CELLA

      Affiliations

    • Evanston Northwestern Healthcare and Northwestern University, Evanston, IL, USA

Abstract 

Quality of life (QOL) is a fundamental consideration for patients with life threatening diseases. Major evolving paradigms are discussed: improved QOL with laparoscopic surgery, the impact on QOL of intraperitoneal chemotherapy for optimally cytoreduced ovarian cancer, combination therapy, sexuality, and survivorship. The goals of treatment for many patients with gynecologic tumors remain largely palliative, and patient reported QOL is the primary outcome determining the utility of treatment. Particularly in this area, QOL endpoints are increasingly important in clinical trials. The QOL issues facing gynecologic cancer patients, the use of validated QOL instruments, recent advances in the evaluation of interventions, and changes in concepts related to QOL are reviewed.

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PII: S0020-7292(06)60040-4

doi:10.1016/S0020-7292(06)60040-4

International Journal of Gynecology & Obstetrics
Volume 95, Supplement 1 , Pages S247-S257, November 2006

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