International Journal of Gynecology & Obstetrics
Volume 99, Supplement 2 , Pages S186-S189, December 2007

Treatment of incomplete abortion and miscarriage with misoprostol

  • J. Blum

      Affiliations

    • Gynuity Health Projects, New York, NY, USA
    • Corresponding Author InformationCorresponding author. Gynuity Health Projects, 15 East 26th Street, Suite 1617, New York, NY 10010, USA. Tel.: +1 212 448 1230; fax: +1 212 448 1260.
  • ,
  • B. Winikoff

      Affiliations

    • Gynuity Health Projects, New York, NY, USA
  • ,
  • K. Gemzell-Danielsson

      Affiliations

    • Division of Obstetrics and Gynecology, Karolinska Institutet/Karolinska University Hospital, Stockholm, Sweden
  • ,
  • P.C. Ho

      Affiliations

    • Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong Special Administrative Region, China
  • ,
  • R. Schiavon

      Affiliations

    • Ipas, Mexico City, Mexico
  • ,
  • A. Weeks

      Affiliations

    • School of Reproductive and Developmental Medicine, University of Liverpool, Liverpool, UK

published online 04 October 2007.

Recommended Dosage

Oral misoprostol 600 μg as a single dose

Abstract 

A literature review was conducted to determine whether misoprostol is an effective treatment for incomplete abortion and, if so, to recommend an appropriate regimen. All English language articles published before October 2007 using misoprostol in at least one of the study arms were reviewed to determine the efficacy of misoprostol when used to treat incomplete abortion in the first trimester. All available unpublished data previously presented at international scientific meetings were also reviewed. Sufficient evidence was found in support of misoprostol as a safe and effective means of non-surgical uterine evacuation. A single dose of misoprostol 600 μg oral is recommended for treatment of incomplete abortion in women presenting with a uterine size equivalent to 12 weeks gestation.

Keywords: Misoprostol, Miscarriage, Incomplete abortion

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PII: S0020-7292(07)00512-7

doi:10.1016/j.ijgo.2007.09.009

International Journal of Gynecology & Obstetrics
Volume 99, Supplement 2 , Pages S186-S189, December 2007