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Volume 101, Issue 1, Pages 94-99 (April 2008)


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Factors associated with acute postpartum hemorrhage in low-risk women delivering in rural India

Stacie E. GelleraCorresponding Author Informationemail address, Shivaprasad S. Goudarb, Marci G. Adamsa, Vijaya A. Naikb, Ashlesha Patelc, Mrutyunjaya B. Belladb, Shobhana S. Pattedb, Stanley A. Edlavitchd, Nancy Mosse, Bhalchandra S. Kodkanyb, Richard J. Dermand

published online 21 February 2008.

Abstract 

Objective

Postpartum hemorrhage (PPH), a major cause of maternal mortality and morbidity in low-income countries, can occur unpredictably. This study examined the sociodemographic, clinical, and perinatal characteristics of low-risk women who experienced PPH.

Methods

This analysis was conducted using data on 1620 women from a randomized trial testing oral misoprostol for prevention of PPH in rural India.

Results

Of the women, 9.2% experienced PPH. No maternal or sociodemographic factors and few perinatal factors differed between women with PPH and those without, other than treatment with misoprostol. Having fewer than 4 prenatal visits and lack of iron supplementation increased the risk for PPH (P<0.001 and P=0.037, respectively). Several factors unknown until the second stage of labor (perineal tear and birth weight) were also associated (P=0.003).

Conclusions

Among women at low risk for PPH, there were few factors associated with further risk. Given that PPH can occur without warning, rural communities should consider ways to increase both primary prevention (iron supplementation, AMTSL) and secondary prevention of PPH (availability of obstetric first aid, availability of transport, and availability of emergency obstetric care).

a University of Illinois, Chicago College of Medicine, Chicago, IL, USA

b Jawaharlal Nehru Medical, College, Belgaum, Karnataka, India

c John H. Stroger Jr. Hospital of Cook County, Chicago, IL, USA

d University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA

e National Institutes of Health, Bethesda, MD, USA

Corresponding Author InformationCorresponding author. Tel.: +1 312 355 0567; fax: +1 312 413 7423.

PII: S0020-7292(08)00004-0

doi:10.1016/j.ijgo.2007.08.025


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