International Journal of Gynecology & Obstetrics
Volume 102, Issue 2 , Pages 124-127, August 2008

Preoperative evaluation of pelvic masses with combined 18F-fluorodeoxyglucose positron emission tomography and computed tomography

  • Yorito Yamamoto

      Affiliations

    • Department of Obstetrics and Gynecology, Kochi Medical School, Kochi, Japan
    • Corresponding Author InformationCorresponding author. Department of Obstetrics and Gynecology, Kochi Medical School, Kohasu, Oko, Nankoku, Kochi 783-8505, Japan. Tel.: +81 88 880 2383; fax: +81 88 880 2384.
    • ,
  • Hiroyoshi Oguri

      Affiliations

    • Department of Obstetrics and Gynecology, Kochi Medical School, Kochi, Japan
    • ,
  • Ruriko Yamada

      Affiliations

    • Department of Obstetrics and Gynecology, Kochi Medical School, Kochi, Japan
    • ,
  • Nagamasa Maeda

      Affiliations

    • Department of Obstetrics and Gynecology, Kochi Medical School, Kochi, Japan
    • ,
  • Shino Kohsaki

      Affiliations

    • Department of Radiology, Kochi Medical School, Kochi, Japan
    • ,
  • Takao Fukaya

      Affiliations

    • Department of Obstetrics and Gynecology, Kochi Medical School, Kochi, Japan

Received 8 February 2008; received in revised form 27 February 2008; accepted 27 February 2008. published online 23 April 2008.

Abstract 

Objective: To prospectively evaluate the diagnostic value of combined 18F-fluorodeoxyglucose position emission tomography and computed tomography (FDG-PET/CT) to discriminate malignant or borderline malignant tumors from benign pelvic masses. Methods: A prospective study of 30 women with suspected ovarian cancer who presented from July 2006 through August 2007. Selection was based on evidence from ultrasound, magnetic resonance imaging, and rising tumor marker levels. All patients underwent FDG-PET/CT prior to standard debulking surgery for a pelvic mass. Results: The sensitivity and specificity of FDG-PET/CT to detect malignant or borderline malignant pelvic tumors were 71.4% and 81.3%, respectively. The sensitivity and specificity of FDG-PET/CT to detect ovarian cancer were 100% and 85.0%, respectively. The maximum standardized uptake value in borderline tumors was significantly lower compared with malignant tumors, but not significantly different compared with benign tumors. Conclusion: FDG-PET/CT had a high diagnostic value in differentiating between malignant and benign tumors, and a low diagnostic value in differentiating between borderline malignant and benign tumors.

Keywords: Borderline malignant tumor, FDG-PET/CT, Ovarian cancer, Pelvic mass

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PII: S0020-7292(08)00116-1

doi:10.1016/j.ijgo.2008.02.019

International Journal of Gynecology & Obstetrics
Volume 102, Issue 2 , Pages 124-127, August 2008

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