Maternal obesity and neonatal congenital cardiovascular defects
Received 6 March 2008; received in revised form 1 May 2008; accepted 2 May 2008. published online 14 July 2008.
Abstract
Objective
To determine whether isolated congenital heart defects (CHDs) were associated with maternal obesity.
Method
In a retrospective study we compared the incidence and severity of isolated CHDs in the offspring of 428 women divided into 3 groups, one of women of normal weight (n=141), one of obese women (n=228), and one of morbidly obese women (n=59) according to their body mass index.
Results
There were 143 mild (66.8%), 44 moderate (20.6%), and 27 complex (12.6%) forms of CHDs in the offspring and septal defects were the most common (61.7%). No significant differences were found among the 3 groups of women regarding the type or severity of CHDs in their respective offspring, or the corrective cardiac surgery required.
Conclusion
No association was found between maternal weight and isolated CHDs in the offspring.
aDepartment of Biostatistics, Epidemiology, and Scientific Computing, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
bDepartment of Obstetrics and Gynecology, Riyadh Military Hospital, Riyadh, Saudi Arabia
Corresponding author. Department of Obstetrics and Gynecology, Riyadh Military Hospital, Riyadh 11431, P.O. BOX 1011, Kingdom of Saudi Arabia. Tel.: +966 1 454 4031; fax: +966 1 453 7462.
ABSTRACT